The raid took place in Purbeck Place in Littlehampton earlier today.
Officers were seen leaving the property, each carrying large bags believed to be filled with Class B drugs.
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The witness suggested that hundreds of plants could have been confiscated during the operation.
Cannabis plants seized in Littlehampton (Image: Sussex News & Pictures)
On Wednesday, February 15, several officers took part in the bust.
Police said the raid was conducted following a tip from the public.
A spokesman for Sussex Police said: “This afternoon following a tip from the public we seized a significant quantity of cannabis plants at a house in Purbeck Place, Littlehampton.
“An investigation has been launched and anyone with any information is asked to contact us online or by calling 101 quoting 601 of 14/02.”
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