Comedy sketches, musical numbers and a special message from the Prince of Wales will be part of the show this evening.
The 2023 program will see AJ Odudu join David Tennant, Joel Dummett, Paddy McGuinness and Zoe Ball as presenters on BBC One.
Among the previously announced sketches will be a parody of the popular BBC show Traitors, starring Dame Mary and Dyer.
The pair will be joined by comedians Jennifer Saunders, Stephen Merchant, Rosie Jones and series one contestants Maddie and Wilf when they gather for the roundtable.
Alternatively, show host Claudia Winkleman will be played by Dawn French before the real traitor is revealed to the audience.
Pop singers Tom Grennan and Zara Larsson will also be performing their new singles during the broadcast from Salford.
Grennan will sing You Are Not Alone, while Swedish singer Larsson will perform her new track Can’t Tame Her.
Other celebrities include pop superstar Kylie Minogue, who will appear in a sketch with the cast of BBC sitcom Ghosts.
Sir Tony Robinson is also set to reprise his famous role as the Black Widow’s goofy sidekick Baldrick to read a bedtime story.
Dermot O’Leary, meanwhile, will team up with Stath Charalambos’ Jamie Demetriou of Stath Lets Flats for a sketch.
Norton, along with Lulu and Sam Ryder, are set to join a mock judging panel where they will be auditioning various celebrities to find the UK’s next Eurovision entrant.
The sketch will feature auditions of varying quality: actor Jamie Dornan, Spandau Ballet star Tony Hadley and comedian Miranda Hart.
Two tickets to the sold-out Eurovision Grand Final will be raffled off as part of Comic Relief’s prize draw.
One winner will also receive a chance to meet Eurovision hosts Rylan and Scott Mills along with tickets, as well as travel expenses and one night’s accommodation at a major hotel in the host city of Liverpool.
All proceeds from the raffle will go to Comic Relief.
The cast of Mrs Doubtfire musical will also give their first UK performance of Make Me A Woman from the new stage show.
The Prince of Wales will appear during the evening’s broadcast as part of a video message in which he meets people receiving help from charities supported by Comic Relief.
For the movieWilliam visited the homeless organization Groundswell.
Comic Relief was founded by Richard Curtis and Sir Lenny Henry in 1985 and this year the fundraiser will support people struggling with the cost of living crisis and tackle issues such as homelessness, mental health issues and food poverty.
Comic Relief 2023 will be broadcast live from Salford’s MediaCity on BBC One on March 17 at 7pm.